The Compounding Pharmacy
a great foundation
Research is showing that vitamin C, vitamin D3 and zinc can help strengthen and modulate the immune system against viral invaders.
Vitamin C (Gown)
- Key for optimal functioning of both innate and adaptive immune system
- Encourages the production of white blood cells
- Powerful antioxidant to mop up oxidative stress
Vitamin D3 (Mask)
- Potent immune system modulator
- Helps the body deal with invaders like viruses
- Helps protect the cardiovascular system
- Improved mood
- Hormone activation such as thyroid hormones
- Key for optimal functioning of both innate and adaptive immune system
- Loss of taste and smell in COVID linked to an acute zinc deficiency
- Increases bioavailability of certain compounds to treat an infection
Viroshield is useful and safe to use in all The 4 Phases of COVID but always check with your doctor before starting any new supplement, especially if you have a comorbidity or are on medication.
Prevention Phase: Support is focused on immune surveillance efficiency and reduction of baseline levels of inflammation, to improve outcomes if the patient becomes infected,
Infection Phase: Support emphasizes immune activity against infection,
Escalating Inflammation Phase:- support is focused on anti-inflammatory measures.
Recovery Phase: Support is focused on resolving inflammation, inhibiting fibrosis and other forms of tissue damage, curtailing losses of function, and restoring and reoptimizing function. People have been observed to relapse into the Escalating Inflammation Phase, so it is essential for clinical surveillance to continue well into what may appear to be the Recovery Phase.
Capsules per container: 60
Serving size: 2 Vegicaps
Servings per container: 30
|Amount Per Serving|
- Read ingredients, dosages and cautions carefully.
- Do not exceed recommended dosages unless on the advice of a healthcare provider.
- If you are on medication, taking nutritional supplements, suffering from any medical condition, pregnant, or breastfeeding, consult your healthcare practitioner before starting any new food, supplement or remedy.
- Do not stop prescribed medication without consulting your healthcare practitioner.
- Report any new or strange symptoms to your healthcare practitioner to ensure appropriate medical care.
- Do not use this product if you are allergic to any of the ingredients.
- Due to the unique nature of each individual person’s health, specific results cannot be guaranteed and may vary from person to person.
- The product information provided is for educational purposes and is not intended as either diagnosis or treatment of any disease, nor does it replace professional medical advice.
- This medicine is not intended to diagnose, treat, cure of prevent any disease.
- Keep out of the reach of children.
- Store in a cool (below 25°c), dry place.
Admission: I have taken this info from Dr Will Cole's site because he has written it so well and to introduce you to him. If you don't already know of Will, I would highly recommend signing up for his informative newsletter and his social pages. Most recently, he is the host of the popular podcast, goop Men.
No other vitamin can hold a candle to vitamin D when it comes to importance and influence on health.
Since vitamin D is fat-soluble, it acts more like a hormone than a vitamin by regulating hundreds of uber-important pathways in your body.
Besides your thyroid hormones, this vitamin is the only other thing every single cell of your body needs in order to function properly.
Also known as the sunshine vitamin, vitamin D is synthesized by your body when your bare skin is exposed to sunlight.
It is impossible to get enough vitamin D from food alone, and unless you live in a very sunny place (like near the equator) and are outside frequently without sunscreen, you are probably deficient.
1. Fights depression
Have you ever noticed how sitting in the sun makes you feel good? The vitamin D activated by that sun exposure acts as an antidepressant in your system, which makes sense when you consider how many people get the “winter blues” coinciding with decreasing amounts of sunshine during the colder months.
2. Reduces asthma
Studies show that pregnant moms with higher vitamin D intake give birth to babies with a 40 percent reduced risk of developing asthma.
Other research suggests that vitamin D has a protective effect against upper-respiratory infections in adults.
3. Balances immunity
Vitamin D is an integral part of your immune system, so it’s no surprise that low levels of vitamin D are associated with autoimmune conditions such as MS, Parkinson’s, type 1 diabetes, inflammatory bowel disorders, and autoimmune thyroid problems (like Hashimoto’s disease and rheumatoid arthritis). Conversely, optimal levels are linked with symptom improvement.
4. Strengthens bones
Just in case you haven’t heard, vitamin D prevents the breakdown of bone and increases the strength of the skeletal system.
5. Boosts brain power
6. Fights cancer
People who have optimal vitamin D levels have lower levels of breast, prostate, colon, ovarian, and pancreatic cancer. There is also some evidence that this vitamin can both kill cancer cells and impede their growth by up to 50 percent!
7. Improves fertility
8. Protects the heart
9. Calms inflammation
Inflammation is the common link between most chronic health problems, and vitamin D is an essential part of the body’s capability to squelch the inflammatory storm going on.
10. Revs up metabolism
In one study, supplementing with D for 12 weeks decreased body fat by 7 percent.
Low levels are also linked to metabolic syndrome, which is a precursor to type 2 diabetes.
11. Enhances physical performance
Supplementing with this important vitamin has been shown to boost muscle strength and physical performance. Vitamin D has also been shown in some studies to increase balance, decreasing falls by 20 percent.
12. Improves sleep
Sleep is so important for feeling and looking your best, and healthy levels of D are associated with better sleep quality.
Ok, vitamin D is super important; so what can I do about it?
Here’s your new vitamin D-boosting lifestyle plan:
1. Test your vitamin D levels.
In functional medicine, we aim for optimally healthy levels (not just within the lab’s reference range), which we consider to be somewhere between 60 and 80, depending on the person.
2. Get some sun.
Spending some time out in the sun, about 20 to 60 minutes (depending on where you live in the world and your skin tone) without sunscreen is a great way to boost your D levels.
3. Eat more vitamin D-rich food.
These are some of favorites:
- Cod liver oil: 1 teaspoon: 440 IU (over 100 percent Daily Value)
- Sardines: 3 ounces: 164 IU (41 percent Daily Value)
- Salmon: 3 ounces: 400 IU (100 percent Daily Value)
- Mackerel: 3 ounces: 400 IU (100 percent Daily Value)
- Tuna: 3 ounces: 228 IU (57 percent Daily Value)
- Raw grass-fed milk: 1 cup: 98 IU (24 percent Daily Value)
- Caviar: 1 ounce: 33 IU (8 percent Daily Value)
- Organic eggs: 1 large: 41 IU (10 percent Daily Value)
- Mushrooms: 1 cup: 2 IU (1 percent Daily Value)
4. Supplement as needed.
Since it’s difficult to get vitamin D exclusively through food, and most of us don’t spend enough time outside in the sun, supplementation may be necessary. Based on where your starting level is, it is suggested to supplement with anywhere between 2,000 and 6,000 IU of vitamin D each day. Because vitamin D is a fat-soluble vitamin, try drops and capsules that include MCT oil or coconut oil, of take either of these oils with your vitamin D3 supplement.
Look for supplements without added fillers or colors.
If you are looking for a vitmain D3 supplement containing higher amounts of D3, please contact me.
5. Tap into vitamin synergy.
When getting your vitamin D levels up to where they should be, it’s best to include the other fat-soluble vitamins: A, E, and K2. These vitamins are uber important in their own right and help balance out the vitamin D, making it more bioavailable but also preventing levels from getting too high. You can supplement with these, but I also suggest focusing on food jam-packed with these fat-soluble vitamins. Check out my article on the subject to learn more.
If you have had your vitamin D tested by your doctor, you'll find that the standard reference range for vitamin D levels falls between 50 and 60 ng/mL. In functional medicine, we aim for an optimal range between 60 and 80 ng/mL. Depending on where your starting levels are, you should be taking anywhere between 2,000 and 6,000 IU of vitamin D per day. Make sure to test your vitamin D levels to find out your starting point, and retest to gauge how your vitamin D level optimization is going. This is a common and easy test and your doctor will likely be fine with it if you ask.
How to incorporate
Since vitamin D is fat-soluble, take advantage of vitamin synergy by combining your supplement with other fat-soluble vitamins, such as A and K2. This will help make it more bioavailable and balanced. It’s also a great idea to take them with fatty foods like avocado, olive oil, wild-caught fish, and coconut to increase their bioavailabiltiy. If you put fats in your daily smoothie (and you should!), this is a good time to pop that vitamin D as well.
It is highly recommended that serum 25(OH)- and 1,25(OH)2-vitamin D be monitored every 60-90 days while consuming this product to ensure that levels remain in an acceptable range. Retest every two or three months to ensure your levels don’t go too high, which isn’t good either.
- Steroids, phenobarbital and dilantin can interfere with vitamin D metabolism
- Orlistat and cholestyramine may interfere with vitamin D absorption
- This product is manufactured in a facility that produces products containing soy, tree nuts, and crustacean shellfish.
- Vitamin C may increase the absorption of iron so it is not recommended if your body has a genetic iron storage issue such as haemochromatosis.
- Vitamin C may increase aluminum absorption from antacids
- Vitamin C may decrease exogenous estrogen metabolism
- Vitamin C may decrease fluphenazine concentrations
- Large doses of vitamin C may reduce half-life of HIV protease inhibitors
- Warfarin activity may be affected by Vitamin C - not recommended for use with Warfarin.
- If you are using medication to lower blood pressure or have a bleeding disorder, consult your healthcare professional before using vitamin C.
- Your body has no way to store this important mineral, so it is important to ensure you’re getting in reguarly through your diet or supplementation.
- Zinc’s main role is to help your body increase white blood cells and fight off infection. It also assists with the release of antibodies.
- Deficiency has been linked to increased instances of sickness so zinc is commonly used for the prevention and treatment of colds and flu.
- Look for supplements that combine the power of vitamin C and zinc.
- Suggested dose - normal: 15 to 30 mg per day.
- Suggested dose - COVID or viral prevention: 30-60mg
- Pregnant women should aim for 12 mg per day since it’s essential for normal fetal development.
How to incorporate
- If you’re eating a healthy well-rounded diet, you should be getting in the proper amount of zinc per day without needing a supplement.
- During winter and flu season, supplementstion might be needed to maintain slightly higher levels for a few months.
- If getting over a cold quickly is your goal, supplementing at least 75 mg per day can reduce cold duration and symptoms so you can get back to your life.
- Zinc may decrease absorption of some antibiotics when taken at same time
- Zinc may increase side effects of cisplatin
- Zinc may decrease the absorption of penicillamine
- Amiloride may increase amount of zinc in body
Zinc plays a crucial role in the function of essentially all immune cells. Deficiency of this critical element has a profound impact on immune response, increasing susceptibility to a variety of infections.208-212
One of zinc’s critical roles in immune function is its role in thymulin production and activity.213
In addition, zinc has specific and well-known antiviral properties.214
Increasing intracellular zinc concentrations in cell culture impairs the replication of a variety of RNA viruses including SARS-CoV-1. Intracellular zinc has been shown to inhibit RNA synthesis by suppressing the SARS-CoV-1 replication and transcription complex.215
In vivo evidence for zinc’s antiviral role comes from a Cochrane review that found zinc intake was associated with a significant reduction in the duration of the common cold. Many of the studies showing benefit when taken during the course of an infection were in the form of a zinc lozenge.216 It makes sense to utilize this mode of delivery during the acute infection phase.
Zinc has also been shown to suppress Th17 cell development.217
Interleukin-17 (IL-17) made by Th17 cells has been shown to drive an inflammatory feedback loop via IL-6 induction.218
Zinc dependent transcription factors are involved in the regulation of the gene expression of IL-6 and TNFα.219
The effect of SNPs in genes encoding zinc transporters on blood zinc levels in humans has been examined.220
Older individuals with gain of function IL-6 SNPs have been shown to have a greater need for zinc.221
Zinc supplement in older individuals with gain of function IL-6 SNPs and low zinc were shown to have lower IL-6 and MCP-1 levels upon zinc supplementation.222
Anosmia (loss of smell) and dysgeusia (distorted sense of taste) are commonly being reported in patients at every phase of COVID-19.223
These are also classic symptoms of zinc deficiency. It is too early in the discovery process to determine if this is cause or effect, nonetheless zinc deficiency greatly impairs immune function, especially resistance to viral infections. Notably, inadequate dietary consumption of zinc is found in almost half the older population.224
208. Shankar, AH, and Prasad, AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr. 1998 Aug;68(2 Suppl):447S-463S. 209. Haase, H, Rink L, Multiple impacts of zinc on immune function. Metallomics.
210. Haase, H, Rink L, Zinc Signals and immune function. Biofactors ((2014) Jan-
211. Dardenne, M. Zinc and immune function. Eur J Clin Nutri. 2002 Aug;56
212. Chasapis, CT, Loutsidou AC, Spiliopoulou, CA, Stefanidou, ME. Zinc and
human health: an update. Arch Toxicol. 2012 Apr;86(4):521-34.
213. Bach JF, Dardenne M. Thymulin, a Zinc-Dependent Hormone. Med Oncol
Tumor Pharmacother. 1989;6(1):25-9.
214. Krenn BM, Gaudernak E, Holzer B, Lanke K, Van Kuppeveld FJM, Seipelt J.
Antiviral Activity of the Zinc Ionophores Pyrithione and Hinokitol against Picornavirus Infections. Journal of Virology Dec 2008, 83 (1) 58-64; DOI: 10.1128/JVI.01543-08
215. te Velthuis AJ, van den Worm SH, Sims AC, Baric RS, Snijder EJ, van Hemert MJ. Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. PLoS Pathog. 2010 Nov 4;6(11):e1001176.
216. Zinc for the common cold. Cochrane Systematic Review (2013) 6. John Wiley and sons, Ltd
217. Kitabayashi C, Fukada T, Kanamoto M, Ohashi W, Hojyo S, Atsumi T, et al. Zinc suppresses Th17 development via inhibition of STAT3 activation. Int Immunol. 2010 May;22(5):375-86.
218. Ogura H, Murakami M, Okuyama Y, Tsuruoka M, Kitabayashi C, Kanamoto M, et al. Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction. Immunity. 2008 Oct 17;29(4):628-36.
219. Mocchegiani E, Costarelli L, Giacconi R, Cipriano C, Muti E, Tesei S, Malavolta M. Nutrient-gene interaction in ageing and successful ageing. A single nutrient (zinc) and some target genes related to inflammatory/immune response. Mech. Ageing Dev. 127, 517–525.
220. Fujihara J, Yasuda T, Kimura-Kataoka K, Takinami Y, Nagao M, Takeshita H. Association of SNPs in genes encoding zinc transporters on blood zinc levels in humans. Leg Med (Tokyo). 2018 Jan;30:28-33.
221. Mocchegiani E, Romeo J, Malavolta M, Costarelli L, Giacconi R, Diaz LE, Marcos A. Zinc: dietary intake and impact of supplementation on immune function in elderly. Age (Dordr). 2013 Jun;35(3):839-60.
222. Mariani E, Neri S, Cattini L, Mocchegiani E, Malavolta M, Dedoussis GV, et al. Effect of Zinc Supplementation on Plasma IL-6 and MCP-1 Production and NK Cell Function in Healthy Elderly: Interactive Influence of +647 MT1a and -174 IL-6 Polymorphic Alleles. Exp Gerontol . 2008 May;43(5):462-71.
223. Vaira LA, Salzano G, Deiana G, De Riu G. Anosmia and ageusia: common findings in COVID-19 patients. Laryngoscope. 2020 Apr 1.
224. Pisano M, Hilas O. Zinc and Taste Disturbances in Older Adults: A Review of the Literature. Consult Pharm. 2016 May;31(5):267-70.